Hadi D Arman Selected Research

Steroid 12-alpha-Hydroxylase (CYP8B1)

1/2022	A synthesis of a rationally designed inhibitor of cytochrome P450 8B1, a therapeutic target to treat obesity.
11/2019	Chemical synthesis of 7α-hydroxycholest-4-en-3-one, a biomarker for irritable bowel syndrome and bile acid malabsorption.
12/2018	Chemical synthesis of 7-oxygenated 12α-hydroxy steroid derivatives to enable the biochemical characterization of cytochrome P450 8B1, the oxysterol 12α-hydroxylase enzyme implicated in cardiovascular health and obesity.

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Hadi D Arman Research Topics

Disease

3	Malaria 01/2022 - 01/2020
3	Obesity 01/2022 - 12/2018
1	Glucose Intolerance 01/2022
1	Body Weight (Weight, Body) 01/2022
1	Weight Gain 01/2022
1	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 11/2019
1	Colorectal Neoplasms (Colorectal Cancer) 01/2017
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 08/2013
1	Skin Neoplasms (Skin Cancer) 08/2013

Drug/Important Bio-Agent (IBA)

4	Biological ProductsIBA 01/2022 - 08/2013
3	artemisinin (artemisinine)IBA 01/2022 - 01/2020
3	Steroid 12-alpha-Hydroxylase (CYP8B1)IBA 01/2022 - 12/2018
2	OxysterolsIBA 11/2019 - 12/2018
2	EnzymesIBA 11/2019 - 12/2018
1	Sucrose (Saccharose)IBA 01/2022
1	Glucose (Dextrose)FDA LinkGeneric 01/2022
1	dihydroartemisinic acidIBA 01/2020
1	Bile Acids and Salts (Bile Acids)IBA 11/2019
1	Biomarkers (Surrogate Marker)IBA 11/2019
1	SteroidsIBA 12/2018
1	trichodermamide AIBA 01/2017
1	trichodermamide BIBA 01/2017
1	QuinoxalinesIBA 08/2013